Cancer mesothelioma – It is a born killer

What is mesothelioma?

The pericardium is the mesothelial tissue that surrounds and acts as a safeguard to the heart. The pleural mesothelium membrane covers the lungs and chest cavity and peritoneum is the mesothelial tissue that enfolds the organs in the abdominal cavity.

What is actually cancer mesothelioma?

Mesothelioma is a type of cancer that affects the mesothelium, a dual layered membrane with which our chest, lungs, abdomen and the heart is wrapped safely.

Cancer Mesothelioma can damage any of these cells, although pleural mesothelioma is more common; it metastasizes and at an advanced stage the disease reach to the other parts of the body like the lymph nodes, lungs, chest wall, or abdominal organs.

How is cancer mesothelioma caused?

Though asbestos exposure is the primary reason in 70% to 80% of the cases, mesothelioma can be caused by other means, like exposure to the chemical zeolite that is also present in asbestos.

Asbestos has become part of our daily life being in cement, brake linings, roof shingles, flooring products, textiles, and insulation. The asbestos fibers take their toll by going into our windpipe and settling in the internal organs causing the formation of carcinogenic tumors.

The overall scenario regarding cancer mesothelioma

Though there is a ban on certain asbestos products, around 1000 people in France and above 2000 people in the U.S are faced with this nightmare each year.

Mostly, workers from shipyards, asbestos mines and mills are prone to this mishap, due to a constant exposure to asbestos. However, it takes 30 to 50 years for the disease to surface and show symptoms though they are not always accurate.

Cancer mesothelioma is proving more than a menace and the average person live for 12-24 months; the earlier it is detected, the better is the cure process.

The recent picture

Today, the U.S. Occupational Safety and Health Administration (OSHA) have put restrictions towards maintaining acceptable levels of asbestos exposure in the workplace. People who work with asbestos are geared up with individual protective equipment to lower their risk of exposure. Even the family members of the workers are prone to the disease, so they are advised to take a shower before leaving for home.

Symptoms of cancer mesothelioma

-    Feeling out of breath and pain in the chest due to an accretion of fluid in the pleura
-    Peritoneal mesothelioma comprises weight loss and abdominal pain and a bulging abdomen due to accumulation of fluid
-    Bowel obstruction, blood clotting abnormalities, anemia, and fever
-    Pain, trouble swallowing, or swelling of the neck or face

However, a registered medical practitioner can diagnose you correctly.

Diagnosis of cancer mesothelioma

Diagnosis commences with an assessment of the patient's medical history, as well as any history of asbestos exposure. A complete physical examination may be performed, including:
-    X-rays of the chest or abdomen
-    A CT (or CAT) scan or an MRI may also be useful. A CT scan is a sequence of comprehensive pictures of areas inside the body created by a computer linked to an X-ray machine
-    In an MRI, a strong magnet connected to a computer is used to draw meticulous pictures of areas affected by cancer mesothelioma inside the body. These pictures are viewed on a monitor and can also be printed
-    A biopsy regarding the taking out of a sample tissue for examination is needed to verify a diagnosis of mesothelioma. Types of biopsy depending on the location of the tumor are thoracoscopy, peritoneoscopy

Lastly, the stage of the disease is important to the doctor for the correct diagnosis.

Cancer mesothelioma treatment

Treatment of cancer mesothelioma yields results depending on the site of the cancer, the phase of the disease, and the patient's physical condition. The usual treatments for cancer mesothelioma are surgery, radiation therapy, and chemotherapy. Occasionally, these treatments are combined.

Surgery is an effective way to remove tumor but the age of the person matters. Radiation therapy and chemotherapy are good ways to ward off the symptoms.

Often, high-end drugs are given to the patient to reduce the fluid formation in body.

Thus, it is better for the workers to get a medical check up at equal intervals and be aware of its symptoms. If a patient is diagnosed with cancer mesothelioma at the earliest stage, the treatments might do wonders for him.

All About a Mesothelioma Lawyer

When someone is diagnosed with mesothelioma, they may find that they need an attorney to help them with their case.  This is a disease that is rare, and there is little to be said about the condition.  The rate of this disease is on the increase and there are new lawyers that are trying to settle many cases for different people.  They have stepped in for the rights of the people to help them with their case.
 
Many victims of this disease need to have a mesothelioma lawyer to help them with their fight.  These lawyers and law firms will deal with the victims and their families to help them claim the right compensation that they deserve from the companies that are responsible for their problems.  These lawsuits result in a lot of money being won by the families when the right lawyer or firm handles them.

Handling asbestos causes mesothelioma.  This comes from working in an environment that is affected by this deadly material or by someone that is contracted to remove it.  Most of the time, the workers are made clear of the dangers that can be caused by working with this type of material.  However, some employers will allow little or no protection from the material when the employees are handling it.  These workers are entitled to compensation for their work.
Today there are many mesothelioma lawyers to choose from and there are many that are right for you.  Many of these lawyers have dealt with this type of suit in the past and know the correct way to handle it.  Those people that are looking for a lawyer should choose someone with a good history and experience in this type of case.  Most lawyers are happy to provide clients with information that may be helpful in using them for your services.  They will show past cases with the names deleted to show proof of their victory.

It is a good idea to find out if the mesothelioma lawyer that you are looking into has won any of their cases or not.  These elements can make all the difference when it comes to trying to find the right lawyer to help you with your situation.  It is a good idea to do as much research as you can on the entire situation.  You may be able to determine your future when you choose their right mesothelioma lawyer for you and your case.

When it comes to being sick with a disease that could have been prevented, it is hard to deal with.  Finding the right mesothelioma lawyer to help you in your fight against these companies is a good start.  You will be fighting for something that means so much to a lot of people and it will be worth it in the end.

10 Options in Treating Mesothelioma

As with any cancer, treatment for Mesothelioma depends on the location of the cancer, the progression of the disease, the age as well as state of health of the patient.

It is the oncologist who specializes in the disease who will decide on the line of treatment. The disease is difficult to treat and in most cases the prognosis is poor. Treatment options include:

1.    If the diagnosis is done in the early stages surgery may be recommended to remove all cancerous tissues. This means thoracoscopy, VATS or video assisted thoracic surgery, mediastinoscopy (used for staging), or laproscopy.  Often, doctors will advise palliative procedures like chest tube drainage and pleurodesis, thoracoscopy and pleurodesis, pleuroperitonial shunt, or pleurectomy, which treat the symptoms of mesothelioma rather than the disease.

2.    Radiation is prescribed aggressively for mesothelioma patients and is often given in combination with surgery or in order to control symptoms, palliatively. Research on using radiation therapy using implants or UV light therapy is in progress as traditional radiation therapy damages surrounding healthy tissue.

3.    Chemotherapy is an option and around 12-20% of patients respond to the drugs. Anti-cancer drugs destroy cancer cells and prevent their spread. In mesothelioma, chemotherapy is not considered to be curative. The aim is to prevent spread of the disease; shrink the tumor prior to surgery, known as neoadjuvant therapy; to annihilate any remains of the tumor in the body post surgery; and to relieve pain and other discomfort, palliative chemotherapy. Experts recommend prescribing premetrexed along with cisplastin. These drugs have shown positive results and this is now standard care for Mesothelioma not treatable by surgery.

4.    Biological therapy using interleukin 2.

5.    Immunotherapy where the body’s own immune system is stimulated to fight the disease. Biological response modifiers, BRMs, are used in treatment. These enhance the functions of the immune system; regulate metabolic reactions that promote growth of cancers; alter cancer cell division; block or reverse processes that lead to formation of cancers; and prevent spread of cancer.

6.    Gene therapy, where attempts are made to correct the gene sequence that causes the cancer. This is of two kinds, replacement gene therapy and knockout gene therapy. 

7.    Administration of lovastatin, a cholesterol lowering drug.

8.    Photodynamic treatment where a photosensitive medication is activated using a laser. This is done during the surgical removal of cancerous tissues.

9.    Draining of fluid in the chest or abdominal cavity followed by introduction of medications into the cavity to prevent fluid accumulation is done for patients who have uncontrolled fluid accumulation and intense discomfort stemming from it.

10.    Combination therapy or Trimodal therapy which means surgery accompanied by radiation and chemotherapy. 

Often, complementary medicines are also used. Termed to be holistic this kind of treatment focuses on a patient’s physical, mental, emotional, and spiritual well being.

In the case of Mesothelioma which is untreatable one can opt for clinical trials of new treatments that are in progress in several research laboratories and centers. The best advice on the line of treatment would be that recommended by the oncologist or physician.

Understanding Chronic Leukemia

Leukemia is a disease of the blood and bone marrow that occurs on the background of genetic predispositions to cancer. Leukemia affects the cellular process of maturation, causing the accumulation of immature blood cells in the spinal marrow and bloodstream. In some cases leukemia causes the incomplete cells to multiply very quickly, while in other cases the abnormal blood cells have prolonged periods of life and persist in different places inside the body. Incomplete blood cells can’t substitute for normal blood cells, as they can’t carry out their roles. The cells affected by leukemia are therefore incompatible with the organism and can cause serious damage.

Judging by the speed of development and the persistence of the disorder, there are two types of leukemia: acute leukemia and chronic leukemia. Judging by the types of stem cells affected by the disorder, leukemia can either be lymphocytic or myelogenous.

Acute leukemia is different from chronic leukemia by the levels that stem cells are able to reach in their development (stem cells that present anomalies still manage to partially develop and either resemble immature cells or complete, normal white blood cells).

Acute leukemia is a form of cancer that develops very rapidly. It is manifested through overpopulation of the blood with immature cells that are unable to fulfill the functions of normal blood cells. In the case of acute leukemia, the marrow is unable to produce normal quantities of red blood cells, white blood cells and platelets. Patients who suffer from leukemia also develop anemia, a deficiency of normal red blood cells. Also, a decreased number of white blood cells reduces the body’s ability of overcoming infections, while the lack of platelets facilitates inflammation and bleeding.

Chronic leukemia tends to develop slower than acute leukemia. In the case of chronic leukemia, the body is able to produce blood cells that are more mature than those produced in acute leukemia. Although these cells may appear incomplete, they can’t fulfill their roles inside the organism and tend to cluster at different levels of the body. They also have a longer period of life.

Chronic leukemia of lymphocytic form is known to affect a type of blood cell called B lymphocyte. The disease weakens the immune system, interferes in the normal activity of the spinal marrow and facilitates the access of harmful cells to body organs. Chronic lymphocytic leukemia first occurs at the levels of the bone marrow, but can quickly spread to different organs and tissue through the bloodstream.

The presence of chronic lymphocytic leukemia is usually revealed by blood tests and careful body examination. Although apparently some people may have no symptoms of the disease, other patients may experience fatigue, lack of concentration, poor balance, memory loss, deterioration of vision and hearing, vertigos, body weakness, joint and bone pains. Just like in other forms of the disease, chronic leukemia requires immediate specific treatment and therapy. The chances of fully overcoming the disease are considerably enhanced if it is discovered quickly.

Understanding and Recognizing Leukemia Symptoms

Leukemia is a sort of cancer of the blood and marrow. The disease is characterized through the overproducing of immature blood cells (stem cells) that aren’t able to fully develop and carry out the activities of normal blood cells.

Each type of mature blood cells has specific traits and roles inside the body. White blood cells or leukocytes have an important role in the immune system, contributing to overcome infections. White blood cells also help in healing flesh wounds and cuts. Red blood cells or erythrocytes contain hemoglobin, which has a great importance in transporting oxygen to the cells within the organism. Red blood cells are vital for the process of cell respiration, carrying oxygen to cells and removing carbon dioxide from them. Platelets have an important role in repairing damage at the level of blood vessels, accumulating to seal any cuts or tares.

Leukemia leads to the accumulation and crowding of diseased stem cells at the level of the bone marrow, which decreases the normal production of healthy blood cells. The lack of normal blood cells leads to the appearance of leukemia symptoms.  It is important to understand that despite the fact that leukemia causes an over production of white blood cells, these cells are immature and can’t substitute for normal blood cells. Due to this, the body is exposed to many forms of infection.

The most common leukemia symptoms are: anemia (insufficient number of red blood cells in the bloodstream), risks of bleeding (insufficient number of platelets in the bloodstream), nose bleeding, bleeding of the oral cavity, predisposition to bruising, high exposure to infections due to lack of white blood cells, improper healing.

Other leukemia symptoms may be fatigue, lack of concentration, poor psychical performance, fever, loss of appetite and weight loss.

In the case of chronic leukemia, which facilitates the accumulation of diseased blood cells in different places inside the body, the leukemia symptoms may be migraines, insomnia, decreased vision and hearing, loss of balance, faints and seizures. Some of these leukemia symptoms need immediate medical intervention, as they may lead to further complications.

Sometimes people with leukemia may have enlarged liver and spleen, causing abdominal swelling or enlarged lymph nodes. The body glands of the organism can also be affected by leukemia.

Leukemia symptoms have a non-specific character. This means that they can be misleading in establishing an appropriate diagnose, as they may also occur in the cases of other diseases. Medical professionals are the only persons able to distinguish leukemia from other illnesses with resembling symptoms. Proper diagnose is very important in order to quickly begin the administration of specific treatment. Blood analysis and careful body examinations can reveal the presence of leukemia. Leukemia is considered to have a high rate of mortality and although the disease can be overcome through treatment and therapy, it can cause death if its presence is not noticed in time. Therefore, prompt intervention is required for leukemia, regardless of its type.

Particularities of Different Types of Leukemia

Leukemia is a form of cancer that occurs at the level of the spinal marrow. Inside the spinal marrow there is a type of immature blood cells that are called stem cells. These cells have a neutral initial state and later develop into different types of blood cells (white blood cells, red blood cells and platelets). Leukemia interferes in the normal process of cell maturation, leading to an accumulation of partially developed blood cells in the marrow, blood and later in body organs. Most of these resulted cells are inefficient inside the organism, as they can’t carry out the activity of normal blood cells.

Depending on to the rate of development, the disease can either be acute leukemia (developing very rapidly), or chronic leukemia (slow developing).  

Particular to acute leukemia is the inability of stem cells (immature cells that can be found within the bone marrow) to reach the state of maturity. These immature blood cells tend to continuously divide and they accumulate in the bloodstream. Acute leukemia develops very rapidly and people who suffer from it need immediate treatment and specific therapy. If mistreated or ignored, acute leukemia causes the death of affected patients within a few months. While certain forms of acute leukemia are usually successfully treated, other forms don’t respond well to the specific treatment.

A characteristic of the chronic type of leukemia is that the diseased cells usually come from more mature cells, but in most cases they aren’t developed normally. The leukemia cells have long periods of life and they tend to accumulate within the bloodstream. Although normal people have between 5000 and 10000 white blood cells in their body, people who suffer from chronic leukemia may have more than 100000.

Lymphocytic and myelogenous types of leukemia are developed from different types of cells:  the lymphocytic type of leukemia develops from cells called lymphoblasts or lymphocytes in the spongious tissue of the bones, while the myelogenous type of leukemia (sometimes refered to as myeloid and myelocytic leukemia) develops from myeloid cells. Judging by the types of cells involved in the development of leukemia and by the rate of cellular division specific to each form of the disease, the main types of leukemia are: acute myelogenous leukemia (AML), chronic myelogenous leukemia (CML), acute lymphocytic leukemia (ALL) and chronic lymphocytic leukemia (CLL).

In addition to the common forms of chronic leukemia, there are also some rare types. Hairy cell leukemia (HCL), just like chronic lymphocytic leukemia, has a slow progression. The cells of hairy cell leukemia are different from other diseased cells mainly through their aspect. Hairy cell leukemia doesn’t usually respond well to treatment.  Prolymphocytic leukemia is a very rare and unusual form of chronic lymphocytic leukemia.

Some cancers, called lymphomas, are caused by abnormal blood cells that are present in the lymph nodes, liver, spleen or other organs. These particular types of cancer don’t occur at the levels of the bone marrow and have a development that is not characteristic to most forms of lymphocytic leukemia.

General Aspects of Leukemia

Many people suffer from leukemia these days. A large number of cases of cancer are identified to be leukemia. Leukemia is a sort of cancer of the blood and marrow. The disease is characterized through the overproducing of immature blood cells (stem cells) that aren’t able to fully develop and to carry out the activities of normal blood cells.

According to their functions and structure, there are three different types of cells within the normal blood: red blood cells, white blood cells and platelets. Through the process of hematopoiesis, these three types of blood cells are developed from a distinctive type of blood cell called stem cell. Stem cells divide and go through several stages of development to finally form a mature blood cell of a particular type, with a certain, distinctive function in the body. The process through which a stem cell morphs into a mature blood cell takes place within the bone marrow.

According to the speed of development and the persistence of the disorder, there are two types of leukemia: acute leukemia and chronic leukemia. Acute leukemia is known to develop very rapidly, while chronic leukemia is developed slowly. According to the types of blood cells affected by the disease, leukemia can either be lymphocytic or myelogenous.

Lymphocytic and myelogenous types of leukemia are developed from different types of cells:  the lymphocytic type of leukemia develops from cells called lymphoblasts or lymphocytes in the spongious tissue of the bones, while the myelogenous type of leukemia (sometimes refered to as myeloid and myelocytic leukemia) develops from myeloid cells.

In the case of acute forms of leukemia, the abnormal cells come from early, immature cells. Such forms of the disorder have a very fast rate of development, due to the fact that normal stem cells tend to multiply frequently. Leukemia cells usually don’t divide faster and more frequently than normal stem cells, they simply don’t stop their process of division when they should. Sometimes the numbers of white blood cells are very high, while in other cases they can be normal or low.

Chronic leukemia, apart from its slow development, is different from acute leukemia by the level of maturation that the diseased cells are able to reach. Stem cells affected by chronic leukemia reach a higher level of maturation but they present abnormalities and they can’t act as healthy white blood cells do. Unlike acute leukemia, in the chronic form of the disease the unhealthy cells have much longer periods of life and they tend to accumulate in different parts of the body.

Leukemia affects people of all age groups. While children usually respond better to the treatment for leukemia and sometimes deal well with the disease, adults difficultly cope with this form of cancer.

Regardless of age and sex, many people are diagnosed with forms of leukemia. Children tend to respond better to some types of leukemia, while adults difficultly cope with the disease. The cases of acute leukemia exceed those of chronic leukemia by approximately 10 percent. Older adults seem to be affected the most by acute leukemia. Around two thirds of acute leukemia cases seem to occur after the age of 60.